Histopathological Observations of The Wound Healing Properties of Plant Exudates of Jatropha curcas Linn

Abstract

This study is aimed at evaluating the wound healing properties of latex exudates of Jatropha curcas Linn based on histopathological observations. The plant is widely known as a source of medicinals for treatment of a variety of ailments. A total of 15 albino Wistar rats of both sexes weighing between 200 and 260gms were used for this study and were divided into three groups; negative control, positive control (Betadine (R)) and exudates of Jatropha curcas. All rats were incised at the flanks on both sides. After treatment, smear biopsies were taken at the hours of 12, 24, 48, 72, 96,144 and 168 for histopathological evaluations. The histopathological parameters used were number of neutrophils, microphages, lymphocytes and fibroblasts. The results showed that there was a significant increase in the numbers of inflammatory cells and fibroblasts suggestive of its ability in acceleration of wound healings.