The Arbotifacent and Cuddling Potencies of Oxytocin in the Wistar Rat Animal Model

Abstract

The anterior pituitary hormone, oxytocin is well reputed for inducing abortion, hastening labor cum parturition, and prepares the subjects for motherhood. The experimental application of this is presently tested in the Wistar rat animal model. Adult female Wistar rats of reproductive age were mated and injected with 0.5ug oxytocin on days 5, 10, 15, 18, 19 and 20 of gestation; hormone potencies and animal behaviors were carefully monitored pre-partum. Oxytocin was least effective in the early days of gestation; however, hormone potencies gradually increased as pregnancy advanced.  Both endogenous secretion and exogenous administration of oxytocin was least effective at the initial and mid-phases of pregnancy in the rat. Perhaps if higher dosage of the hormone were administered, the resulting high plasma concentration might probably override the prevailing physiology in the early phase of pregnancy in the uterus though, and such could be effective enough to elicit response possibly, with the accompanied complications.